Abstracts supporting the safety and efficacy of SpaceOAR hydrogel.


Rectal Balloon vs. Injectable Spacer Gel

Dosimetric comparison of rectal-sparing capabilities of rectal balloon vs injectable spacer gel in stereotactic body radiation therapy for prostate cancer: lessons learned from prospective trials.

Phase 3 Trial Data Show Use of SpaceOAR® Hydrogel Helps Maintain Erectile Function Following Prostate Cancer Radiation Treatment

An abstract accepted at the ASCO 2017 Genitourinary Cancer Symposium showed that SpaceOAR hydrogel, placed between the prostate and rectum in men undergoing prostate radiotherapy, helps men maintain sexual function and potency following intensity modulated radiation therapy (IMRT).

Evaluation of Sexual Function On A Randomized Trial of a Prostate/Rectal Spacer

Hamstra D, et al. 2017 Genitourinary Cancers Symposium, J Clin Oncol 35, 2017 (suppl 6S; abstract 69)

Dosimetric Consequences and Acute Toxicity Following Perirectal Hydrogel Spacer Injection During Permanent Prostate Brachytherapy

J. Kahn, et al. 2016 ASTRO International Journal of Radiation Oncology*Biology*Physics, Volume 96, Issue 2, Supplement, 1 October 2016, Page E226

Reduction in Rectal Dose in Prostate Cancer Patients Using Hydrogel Spacer During Proton Therapy

Jesse Conterato, BA (Northwestern Medicine Chicago Proton Center) - at the PTCOG-NA October 2016

Comparison of hydrogel spacer and rectal immobilization on intra-fraction motion equivalence using image guidance prostate proton therapy

Rachel Rendall, BS (Northwestern Medicine Chicago Proton Center) at the PTCOG-NA October 2016

Continued Benefit to Rectal Separation for Prostate RT: Final Results of a Phase III Trial

D. A. Hamstra et al, 2016 ASTRO Annual Meeting - Late-breaking Abstract

Clinical and Dosimetric Aspects of Prostate Cancer Patients Treated with Pencil Beam Scanning (PBS)

Proton Therapy Utilizing Hydrogel Rectal Spacer.
Fagundes M, et al. Poster – PTCOG 2016 Prague

Effect of Hydrogel Spacer On Achievable Rectal DVH for IMRT in Prostate Cancer

Bosch W., et al. Presented at AAPM 2015, TH-AB-BRB-9

Model-based prediction of rectal toxicity reduction in prostate cancer IMRT with hydrogel rectum spacer

Vanneste B., et al, Presented at 3rd ESTRO Forum 2015, #690, EP-1233

The Introduction of Advanced Biomaterials for Use in Urologic Procedure

Robert Grubb III et al. Moderated Poster AUA EUS 2014

Acute Rectal Toxicities for 180 Prostate Carcinoma Patients Administered Spacer Material in Conjunction With Radiation Therapy

L. Barnes, et al. Presented at ASTRO 2013 International Journal of Radiation Oncology * Biology * Physics Vol. 87, Issue 2, Supplement, S173

Learning Curve in the Application of a Hydrogel Spacer to Protect the Rectal Wall During Radiation Therapy of Localized Prostate Cancer

M. Pinkawa, et al. Presented at ASTRO 2013 – International Journal of Radiation Oncology* Biology * Physics , Volume 87, Issue 2, Supplement , Page S348, 1 October 2013.

Phase I study of Stereo-Ablative Radiotherapy with the use of SpaceOAR hydrogel as Definitive Treatment of Prostate Cancer. Preliminary Experience.

A. Tagliagambe et al. Presented at ASTRO 2013 International Journal of Radiation Oncology * Biology * Physics Vol. 87, Issue 2, Supplement, Page S370

Polyethylene glycol hydrogel spacer use significantly reduces rectal radiation dose in patients undergoing high dose rate prostate brachytherapy

Malouf D, et al. BJU International – Special Issue: Abstracts of the Prostate Cancer World Congress & 14th Australasian Prostate Cancer Conference, Melbourne, Australia, 6–10 August 2013 Volume 112, Issue Supplement S1.

Bowel toxicity after IMRT for prostate cancer with a spacer gel – a matched-pair comparison

Pinkawa M, et al. Presented at ESTRO, Barcelona, Spain 2012

Hydro-Dissection Technique for Fast and Safe Transperineal Spacer Injection

Hatiboglu G, et al. Presented at SIU, Berlin, Germany. October 2011

The Use of an Injectable Spacer Material in Conjunction With High Dose-Rate Brachytherapy for Prostate Cancer

Tokita KM, et al. Presented at ABS San Diego, California, USA April 2011

The Use of an Injectable Tissue Spacer in Conjunction With Adaptive Radiotherapy for Prostate Cancer

Harrison JA, et al. et al. Presented at the Cancer Imaging and Radiation Therapy Symposium, Atlanta, Georgia, USA April 2011