SpaceOAR® Hydrogel Clinical Publications

35,000+ Prostate Cancer Patients Treated and Over 60 Clinical Publications

Stereotactic body radiotherapy with periprostatic hydrogel spacer for localized prostate cancer: toxicity profile and early oncologic outcomes

Source: Radiation Oncology (2019); 14(1): 136 Author: Hwang, ME et al.
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Optimization of prostate cancer radiotherapy using of a spacer gel, volumetric modulated arc therapy and a single biological organ at risk objective.

Source: International Journal of Radiation Research (2018); 16(2) Author: Pinkawa, M et al.
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Phase 2 Multicenter Study of Gantry-Based Stereotactic Radiotherapy Boost for Intermediate and High Risk Prostate Cancer (PROMETHEUS)

Source: Frontiers in Oncology (2019) Author: Pryor, D et al.
  • Intermediate and high-risk prostate cancer patients treated across five centers with gantry-based SBRT
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High dose rate brachytherapy boost for prostate cancer: Biochemical control and the impact of transurethral resection of the prostate and hydrogel spacer insertion on toxicity outcomes

Source: Journal of Medical Imaging and Radiation Oncology (2019) Author: Chao, M et al.
  • Retrospective single-center study in Australia examining the safety and effectiveness of HDR-BT combined with EBRT in intermediate and high-risk prostate cancer patients

 

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Maximizing rectal dose sparing with hydrogel: A retrospective planning study

Source: Journal of Applied Clinical Medical Physics (2019) Author: Paetkau, O et al.
  • SpaceOAR™ Hydrogel resulted in significant reductions in rectal dose regardless of planning and contouring technique
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Rectum-spacer related acute toxicity – endoscopy results of 403 prostate cancer patients after implantation of gel or balloon spacers

Source: Radiation Oncology (2019); 14(47) Author: Schörghofer, A et al.
  • Patients of all risk groups were included
  • Overall rectal toxicity was very low and acute grade 2 toxicity directly related to the implantation procedure was seen exclusively in patients who had received the spacer balloon

 

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Improving rectal dosimetry for patients with intermediate and high-risk prostate cancer undergoing combined high-dose-rate brachytherapy and external beam radiotherapy with hydrogel space

Source: Journal of Contemporary Brachytherapy (2019) Author: Chao, M et al.
  • Intermediate and high-risk prostate cancer patients undergoing combined HDR brachytherapy and EBRT
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SpaceOAR to improve dosimetric outcomes for monotherapy high-dose-rate prostate implantation in a patient with ulcerative colitis

Source: Journal of Contemporary Brachytherapy (2018); 10(6): 577-582. Author: Trager, M et al.
  • Single patient HDR brachytherapy experience resulted in successful SpaceOAR hydrogel implant in patient with ulcerative colitis
  • Results from case studies are not necessarily predictive of results in other cases. Results in other cases may vary.
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SpaceOAR Hydrogel Placement in Patients Undergoing Proton Therapy and Low-Dose-Rate Brachytherapy

Source: Journal of Interventional Radiology (1)2 Author: Ellis R et al.
  • Case report of combination modality therapy using ADT and proton therapy followed by an LDR brachytherapy boost
  • Results from case studies are not necessarily predictive of results in other cases. Results in other cases may vary.
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Ano-rectal wall dose-surface maps localize the dosimetric benefit of hydrogel rectum spacers in prostate cancer radiotherapy

Source: Clinical & Translational Radiation Oncology (2018); 14: 17-24 Author: Vanneste, B.G.L et al.
  • Dose constraints can be improved for current clinical treatment planning
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